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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16960 | Sultiame | Others , Carbonic Anhydrase | |
Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research. | |||
T0515 | Tioxolone | Carbonic Anhydrase | |
Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor. | |||
T8827 | EMAC10101d | Carbonic Anhydrase | |
compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range. | |||
T4321 | Indisulam | E 7070 | CDK , Carbonic Anhydrase |
Indisulam (E 7070) is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in th... | |||
T0782 | Benzthiazide | Aquatag,Lemazide,Dihydrex | Carbonic Anhydrase |
Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted ... | |||
T2187 | Orthanilamide | O-Aminobenzenesulfonamide,Benzenesulfonamide,O-Sulfanilamide | Carbonic Anhydrase , Autophagy |
Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline. | |||
T6469 | Dichlorphenamide | Diclofenamide,Daranide,Antidrasi | Carbonic Anhydrase |
Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma. | |||
T6581 | Methyclothiazide | Duretic,Enduron,Aquatensen | Others , Carbonic Anhydrase |
Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease. | |||
T6781 | Benzenesulfonamide | Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide | Carbonic Anhydrase |
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases. | |||
T36758 | CAIX Inhibitor S4 | S4 | Carbonic Anhydrase |
CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM. | |||
T4S2354 | Dimethylfraxetin | Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin | Carbonic Anhydrase |
Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki:0.0097 μM) | |||
T0142 | Brinzolamide | AL-4862 | Carbonic Anhydrase |
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor. | |||
T21294 | Polmacoxib | CG-100649,CG100649,CG 100649 | COX , Carbonic Anhydrase |
Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through... | |||
T0106 | Methazolamide | L584601,CL 8490 | Carbonic Anhydrase |
Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma. | |||
T5012 | Ethoxzolamide | PNU-4191,Redupresin,L-643786 | Antibacterial , Carbonic Anhydrase |
Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor. | |||
T23782 | Benzolamide | CL-11366,W 1803,CL 11366,CL11366,W-1803 | Carbonic Anhydrase |
Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons. | |||
T2017 | U-104 | NSC-213841,MST-104 | Carbonic Anhydrase |
U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM). | |||
T0267 | Zonisamide | AD 810,CI 912 | Calcium Channel , Sodium Channel , Carbonic Anhydrase |
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms... | |||
T6503 | Fluorometholone Acetate | NSC 47438,Flarex,Eflone,Oxylone acetate | Glucocorticoid Receptor , Carbonic Anhydrase |
Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye. | |||
T0675 | Topiramate | RWJ 17021,McN 4853 | Potassium Channel , Calcium Channel , GABA Receptor , Sodium Channel , GluR , Carbonic Anhydrase , iGluR |
Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures. Topiramate has been rarely associated with hepatic injury and largely when used in combination ... |